My initial source for this individual comes from Bill Hagan (email 28 June 2009). Source includes material from Families of Early Jessamine county, Kentucky:

Boyds from the book Pioneer Life Autobiography and Sermons of Elder Elijah Martindale also Pioneer History of the Boyd Family Belle Stanford, 1892 published in Indianapolis, Indiana by Carlon and Hollenbeck, Printers.

Isabella Higgins, wife of Samuel Boyd, was born in South Carolina, February 13, 1764. Her father, John Higgins was a native of Scotland. Her mother's name was Elizabeth Campbell. She was also of Scotch-Irish descent . Samuel Boyd and Isabella Higgins were married in 1785. She was named in honor of the queen of Spain, and also had the honor of being escorted by Andrew Jackson in her youthful days. Her love settled on the one-eyed soldier of the revolution, who was an honest farmer and afterward became a faithful pioneer preacher. They first became members of the Presbyterian Church and afterward joined the Newlights. It was favorable for their vast progeny that they were inclined to go westward and seek more productive soil. Soon after their marriage, they moved to Tennessee and settled in a cabin home. While living there a great shadow fell across their pathway. One of Isabella's cousins in Carolina married a somewhat wealthy man and they arranged to visit their cousin in her new home in Tennessee. The road they were to travel was hilly, or rather mountainous, and unfrequented. At that time the only mode of travel was by horseback. They made their visit, but soon after they set out on their return trip they were murdered and their bodies left lying in the forest. Their saddles were left lying beside them, but they had been robbed and their horses taken. This left a sad memory on the minds of the youthful pioneers. They moved from Tennessee and settled in Madison County, Kentucky.
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As a young women, Isabella danced with Andrew Jackson. (History of Wayne County, page 238)